Search results for "Proline benzyl ester"

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On the enhancement of stereoselection by cooperation between chiral auxiliaries. Asymmetric diels-alder reactions with fumaric acid bis ((S)-proline …

1989

Abstract Fumaric acid bis ((S)-proline benzyl ester) amide reacts with cyclopentadiene in thermal and Lewis acid catalyzed Diels-Alder reactions to give the cycloadducts with high yields and diastereomeric ratios up to 100:1.

Fumaric acidCyclopentadieneOrganic ChemistryDiastereomerBiochemistryCatalysischemistry.chemical_compoundchemistryAmideDrug DiscoveryDiels alderOrganic chemistryLewis acids and basesProline benzyl esterTetrahedron Letters
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ChemInform Abstract: (S)-Proline Benzyl Ester as Chiral Auxiliary in Lewis Acid-Catalyzed Asymmetric Diels-Alder Reactions.

1989

Asymmetric Diels-Alder reaction of cyclopentadiene (I) with (S)-proline benzyl ester (II) yields a mixture of the diastereomeric cycloadducts (R)-(III) and (S)-(IV).

chemistry.chemical_classificationchemistry.chemical_compoundChiral auxiliaryCyclopentadienechemistryDiels alderDiastereomerGeneral MedicineLewis acids and basesProline benzyl esterBridged compoundsMedicinal chemistryCatalysisChemInform
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